Diabetic Peripheral Neuropathy is nerve damage caused by chronically high blood sugars and diabetes. It leads to numbness, loss of sensation, and sometimes pain in feet, legs or hands. It is the most common complication of diabetes. Chronically high blood sugar levels damage nerves. The damaged nerves cannot effectively carry messages between brain and other parts of the body. This means you may not feel heat or cold or pain in your feet, legs, or hands.