
Compensation
Up to $1,875
For completed office visits and diagnostic testing
Osteoarthritis of the Knee Clinical RESEARCH study
Living with knee osteoarthritis?
If you’re age 50 or older and have knee osteoarthritis (OA), you may be eligible to join a clinical research study at Clinical Research of West Florida (CRWF). By volunteering, you can help researchers learn more about potential new treatment options—while receiving study-related care at no cost and compensation for your time and participation.
Check your eligibility, learn about the study process, and see how you can help advance the future of osteoarthritis care. Sign up below to get started!
What is Osteoarthritis of the Knee?
Osteoarthritis (OA) of the knee is a common form of arthritis that develops when the cartilage that cushions the knee joint gradually wears down over time. As cartilage thins, the bones in the joint may rub against each other, leading to pain, stiffness, swelling, and reduced mobility.
Knee osteoarthritis is often described as a “wear and tear” type of arthritis. It can become more common with age and may also be linked to previous injuries, repetitive strain on the joint, genetics, or carrying extra weight that increases pressure on the knees.

two Convenient pinellas county locations
Study Locations
2147 NE Coachman Road
Clearwater, FL 33765
727-466-0078
605 N. Howard Ave.
Tampa, FL 33606
813-870-1292
Protocol: PARA_OA_012 | Indication: Osteoarthritis of the Knee
What To Know About Volunteering For One Of Our Osteoarthritis of the Knee Clinical Trials
Clinical trial participation is always voluntary, and you can withdraw at any time. The process is designed to be clear, supportive, and centered around your comfort and safety. It typically starts by identifying a study you may qualify for, speaking with the study team to review eligibility, signing an informed consent form, completing screening tests, and enrolling in the study if you’re a match.
This Osteoarthritis of the Knee study includes approximately 25 office visits over about 65 weeks.
want to learn more?
More About Osteoarthritis of the Knee
Osteoarthritis is a progressive condition, meaning symptoms can increase over time. Many people start with occasional discomfort, but as the joint changes, pain may become more frequent and daily tasks may feel harder—like walking longer distances, getting up from a chair, or going up and down stairs.
The symptoms of OA can vary, but typical signs include:
- Knee pain during walking, standing, or climbing stairs
- Stiffness, especially in the morning or after sitting
- Swelling or tenderness around the joint
- A feeling of grinding, clicking, or popping in the knee
- Reduced range of motion or difficulty with daily activities
While treatments such as exercise, physical therapy, medications, injections, and lifestyle changes can help manage symptoms, clinical research is essential for discovering new approaches that may reduce pain, improve function, and support long-term joint health.
If you have knee osteoarthritis and are looking for options, participating in a clinical trial may be a meaningful way to explore study-related care and support future treatment advances.
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